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Stevens-Johnson Syndrome (SJS) and Toxic Epidermal Necrolysis (TEN) Litigation

Even prescription medications that most people believe to be "safe" can cause severe illness and death. Among the most serious of these illnesses are Stevens-Johnson Syndrome (SJS) and toxic epidermal necrolysis (TEN). These life-threatening skin diseases are most often associated with certain drugs. These drugs include certain antibiotics, seizure medicines, and common nonsteroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen.

What Are SJS and TEN?

SJS and TEN are two forms of a life-threatening skin disease that cause rashes, skin peeling and sores on the mucous membranes.

SJS and TEN usually begin with fever, headache, cough and body aches. A red rash subsequently breaks out on the face and trunk. It often spreads to the rest of the body in an irregular pattern. The areas of rash enlarge and spread. Many form blisters at their center.

In SJS, blisters of mucous membranes usually develop in the mouth, throat, eyes, anus and genitals. There are also patchy areas of rash. Sometimes the mucous membranes of the digestive and respiratory tracts are involved, resulting in diarrhea and difficulty in breathing.

Like SJS, TEN also involves blistering of mucous membranes. In addition, the entire top layer of the skin peels off (sloughs) in sheets from large areas of the body. In many people, 30 percent or more of the body’s surface peels away. The affected areas are painful, and the person feels very ill with chills and fever. In some people, the hair and nails fall out. The skin loss in TEN is similar to a severe burn and is equally life threatening. Huge amounts of fluids and salts can seep from the large, raw, damaged areas. A person who has this disorder is very susceptible to severe infection at the sites of damaged, exposed tissues.

Both SJS and TEN cause severe organ damage, permanent disfigurement and death.

What Medications Are Linked to SJS and TEN?

Nearly all cases of SJS and TEN are caused by a reaction to a drug. The list to the right includes some of, but not all, antibiotics, seizure medications, and NSAIDs that have been linked to SJS and TEN.

How Does Waters & Kraus Help Families Affected by SJS and TEN?

Our firm has worked with numerous families facing the devastating side effects of these life-threatening illnesses. We understand the scientific evidence as well as the emotional and financial implications in dealing with SJS and TEN, and are committed to easing the tragedy of these illnesses through competent representation and litigation.

To learn more about our representation or the firm's resources, or to have a Waters & Kraus SJS attorney review your case, email us.

Medications linked to SJS and TEN

Advil® (ibuprofen)
Aleve® (naproxen)
Amigesic® (salsalate)
Amoxicillin (penicillin)
Anacin® (salicylate)
Anaflex® 750 (salsalate)
Anaprox® (naproxen)
Ansaid® (flurbiprofen)
Arthritab® (sodium salicylate)
Arthropan® (choline salicylate)
Arthrotec® (diclofenac)
Ascriptin® (acetylsalicylic acid)
Bayer® (sodium salicylate)
Bayer® Select (magnesium salicylate)
Bextra® (valdecoxib)
(prior to 2004)
Bufferin® (acetylsalicylic acid)
Cataflam® (diclofenac)
Celebrex® (celecoxib)
Children’s Advil® (ibuprofen)
Children’s Motrin® (ibuprofen)
Clinoril® (sulindac)
Daypro® (oxaproxen)
Diflunisal (generic for Dolobid®)
Disalcid® (salsalate)
Doan’s® Pills (sodium salicylate)
Dolobid® (diflunisal)
Ecotrin® (acetylsalicylic acid)
Excedrin® (ibuprofen)
Feldene® (piroxicam)
Indocin® (indomethacin)
Indocin® SR (indomethacin)
Lodine® (etodolac)
Lodine® XL (etodolac)
Magan® (magnesium salicylate)
Marthritic® (salsalate)
Meclomen® (meclofenamate)
Mobic® (meloxicam)
Mobidin® (magnesium salicylate)
Mobigesic® (magnesium salicylate)
Monogesic® (salsalate)
Motrin® (ibuprofen)
Motrin® IB (ibuprofen)
Nalfon® (fenoprofen)
Naprelan® (naproxen)
Naprosyn® (naproxen)
Nuprin® (ibuprofen)
Orudis® (ketoprofen)
Orudis® KT (ketoprofen)
Oruvail® (ketoprofen)
Ponstel® (mefenamic acid)
Prilosec® (omeprazole)
Quinolone antibiotics (floxins)
Relafen® (nabumetone)
Salflex® (salsalate)
Sodium salicylate (available only as a generic)
Salsitab® (salsalate)
Tolectin® (tolmetin)
Topamax® (topiramate)
Tricosal® (choline and magnesium salicylate)
Trilisate® (choline and magnesium salicylate)
Vioxx® (rofecoxib)
Voltaren® (diclofenac)
Voltaren® XR (diclofenac)
Zithromax® (azithromycin)
(Canada only)